ANTIMICROBIAL ACTIVITY OF AROMA CHEMICALS AGAINST UROPATHOGENS
Tripti Malik, Padma Singh
The purpose of the study was to evaluate the antimicrobial activity of some aroma chemicals, namely, β- citronellol, citronellyl formate, trans-geraniol and l- linalool, which are also known to be the major components of P.graveolens essential oil. The antimicrobial activity of chemicals was determined against both antibiotic sensitive and resistant uropathogens using the disc diffusion method. Minimum inhibitory concentration and minimum lethal concentration was also determined by broth microdilution method. The anti-swarming effects in Proteus mirabilis isolates were also determined in the terms of inhibition of swarm fronts. The antimicrobial activity was determined to be concentration dependent; the best inhibitory activity was shown by trans-geraniol, followed by citronellyl formate and l-linalool. Trans-geraniol also highly inhibited the diameter of both the swarm fronts. The inhibitory effects of these aroma chemicals indicate their promising candidature for developing newer anti-microbial agents/drugs.